Optimum Nutrition
THE BIOHACKING STANDARD
Welcome to our store
Couldn't load pickup availability
Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
Fadogia agrestis is a Huberman-podcast-popularized herb with zero human RCT data and legitimate hepatic and testicular-toxicity signals in rat studies (Yakubu 2005, Yakubu 2008). Tongkat Ali has better human evidence (Talbott 2013 for stress/testosterone with Physta extract) but NusaPure doesn't specify the Physta or LJ100 standardization. Combined product carries real safety concerns; would not recommend to users. Would move to Standard 62+ if Fadogia removed and Tongkat kept at named-source (Physta) 200-400mg.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
Auto-generated from Vyvata's scoring data for this product. For general questions about the store (shipping, returns, wholesale), see the site FAQ.
NusaPure Fadogia Agrestis 600mg + Tongkat Ali 400mg - 150 Veggie Caps - Non-GMO, Made in USA, Serving 2 VCaps, BioPerine is a product from NusaPure, categorized under Men's health in the Supplements vertical. It is scored on the Vyvata Scoring Framework — an independent 6-dimension rubric applied uniformly to every product Vyvata lists.
52/100 overall — Rejected tier (0–49 band). Per-dimension breakdown: Transparency 60, Formulation 55, Manufacturing 55, Sustainability 55, Safety 45, Evidence 40. Scored as of 2026-08-24.
Fadogia agrestis is a Huberman-podcast-popularized herb with zero human RCT data and legitimate hepatic and testicular-toxicity signals in rat studies (Yakubu 2005, Yakubu 2008). Tongkat Ali has better human evidence (Talbott 2013 for stress/testosterone with Physta extract) but NusaPure doesn't specify the Physta or LJ100 standardization. Combined product carries real safety concerns; would not recommend to users. Would move to Standard 62+ if Fadogia removed and Tongkat kept at named-source (Physta) 200-400mg.
Strongest: Transparency at 60/100 (dose disclosure vs proprietary blends, and honesty of marketing claims) and Formulation at 55/100 (dose adequacy, bioavailability form, and ingredient redundancy). Weakest: Safety at 45/100 (adverse-event profile, interaction risk, and dose ceiling) and Evidence at 40/100 (quality of published RCT support for the active ingredients at the label dose). All six dimensions feed the overall Vyvata score; a weakness on any one dimension pulls the overall down proportionally.
No third-party certifications (NSF, USP, ConsumerLab, or equivalent) were on record at the time of scoring. This affects the Manufacturing dimension score. The manufacturer may test internally or have obtained certification more recently — check the current product label for the most up-to-date information.
Would move to Standard 62+ if Fadogia removed and Tongkat kept at named-source (Physta) 200-400mg.
The top-ranked men's health product in the Vyvata catalog is currently Ritual Essential for Men 18+ at 72/100. See the full ranked list of 156 scored products in this subcategory at https://vyvata.com/pages/best-men-s-health-supplements-ranked.
The Vyvata Scoring Framework rates every listed product 0–100 across six dimensions: Evidence, Formulation, Manufacturing, Safety, Transparency, and Sustainability. Tier bands: Elite 85–100 (top-tier evidence + formulation + manufacturing), Verified 70–84 (strong on most dimensions), Standard 50–69 (solid but with weaknesses called out), Rejected 0–49 (specific failures documented). Rejected products remain listed with reasons. Full methodology at https://vyvata.com/pages/methodology.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. For customer reviews and community discussion, search external platforms directly: Amazon (https://www.amazon.com/s?k=NusaPure%20NusaPure%20Fadogia%20Agrestis%20600mg%20%2B%20Tongkat%20Ali%20400mg%20-%20150%20Veggie%20Caps%20-%20Non-GMO%2C%20Made%20in%20USA%2C%20Serving%202%20VCaps%2C%20),Google(https://www.google.com/search?q=NusaPure%20NusaPure%20Fadogia%20Agrestis%20600mg%20%2B%20Tongkat%20Ali%20400mg%20-%20150%20Veggie%20Caps%20-%20Non-GMO%2C%20Made%20in%20USA%2C%20Serving%202%20VCaps%2C%20+reviews),Reddit(https://www.reddit.com/search/?q=NusaPure%20NusaPure%20Fadogia%20Agrestis%20600mg%20%2B%20Tongkat%20Ali%20400mg%20-%20150%20Veggie%20Caps%20-%20Non-GMO%2C%20Made%20in%20USA%2C%20Serving%202%20VCaps%2C%20%20review),andTrustpilot(https://www.trustpilot.com/search?query=NusaPure%20NusaPure%20Fadogia%20Agrestis%20600mg%20%2B%20Tongkat%20Ali%20400mg%20-%20150%20Veggie%20Caps%20-%20Non-GMO%2C%20Made%20in%20USA%2C%20Serving%202%20VCaps%2C%20).Vyvatadoesnotaggregate,republish,orlicensethosethird-partyreviews.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

Optimum Nutrition
Onnit
WOW MD LLC
Prevagen
Find Your Protocol
A few quick questions about your goals and current concerns. We'll build a tailored protocol — a Basics list of essentials plus a comprehensive Biohackers list — across all Vyvata categories.
No signup required · Your protocol is private to you