Optimum Nutrition
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Phyllanthus niruri (chanca piedra) is traditionally used for kidney and gallstones, but the clinical trial base is thin and mixed — a Cochrane-style review (Freitas 2002) is inconclusive and later trials show minimal stone-passage effect. The 200 mg 10:1 extract with BioPerine is a coherent formulation, but the underlying evidence does not warrant Standard tier in a transparency-first rubric. Would move to Standard 60+ if positioned solely as urinary support with no stone-clearing implication.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
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NusaPure Chanca Piedra 200mg | 200 Veggie Caps | Herbal Extract Supplement | Extract 10:1, Non-GMO, Bioperine | 100 Servings per Bottle is a product from NusaPure, categorized under Gut health & digestive support in the Supplements vertical. It is scored on the Vyvata Scoring Framework — an independent 6-dimension rubric applied uniformly to every product Vyvata lists.
52/100 overall — Rejected tier (0–49 band). Per-dimension breakdown: Safety 60, Formulation 55, Manufacturing 55, Transparency 55, Sustainability 55, Evidence 48. Scored as of 2026-08-24.
Phyllanthus niruri (chanca piedra) is traditionally used for kidney and gallstones, but the clinical trial base is thin and mixed — a Cochrane-style review (Freitas 2002) is inconclusive and later trials show minimal stone-passage effect. The 200 mg 10:1 extract with BioPerine is a coherent formulation, but the underlying evidence does not warrant Standard tier in a transparency-first rubric. Would move to Standard 60+ if positioned solely as urinary support with no stone-clearing implication.
Strongest: Safety at 60/100 (adverse-event profile, interaction risk, and dose ceiling) and Formulation at 55/100 (dose adequacy, bioavailability form, and ingredient redundancy). Weakest: Sustainability at 55/100 (sourcing practices, packaging, and corporate practice) and Evidence at 48/100 (quality of published RCT support for the active ingredients at the label dose). All six dimensions feed the overall Vyvata score; a weakness on any one dimension pulls the overall down proportionally.
No third-party certifications (NSF, USP, ConsumerLab, or equivalent) were on record at the time of scoring. This affects the Manufacturing dimension score. The manufacturer may test internally or have obtained certification more recently — check the current product label for the most up-to-date information.
Would move to Standard 60+ if positioned solely as urinary support with no stone-clearing implication.
The top-ranked gut health & digestive support product in the Vyvata catalog is currently Microbiome Labs MegaSporeBiotic Probiotics for Women & Men at 75/100. See the full ranked list of 316 scored products in this subcategory at https://vyvata.com/pages/best-gut-health-and-digestive-support-supplements-ranked.
The Vyvata Scoring Framework rates every listed product 0–100 across six dimensions: Evidence, Formulation, Manufacturing, Safety, Transparency, and Sustainability. Tier bands: Elite 85–100 (top-tier evidence + formulation + manufacturing), Verified 70–84 (strong on most dimensions), Standard 50–69 (solid but with weaknesses called out), Rejected 0–49 (specific failures documented). Rejected products remain listed with reasons. Full methodology at https://vyvata.com/pages/methodology.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. For customer reviews and community discussion, search external platforms directly: Amazon (https://www.amazon.com/s?k=NusaPure%20NusaPure%20Chanca%20Piedra%20200mg%20%7C%20200%20Veggie%20Caps%20%7C%20Herbal%20Extract%20Supplement%20%7C%20Extract%2010%3A1%2C%20Non-GMO%2C%20Bioperine%20%7C),Google(https://www.google.com/search?q=NusaPure%20NusaPure%20Chanca%20Piedra%20200mg%20%7C%20200%20Veggie%20Caps%20%7C%20Herbal%20Extract%20Supplement%20%7C%20Extract%2010%3A1%2C%20Non-GMO%2C%20Bioperine%20%7C+reviews),Reddit(https://www.reddit.com/search/?q=NusaPure%20NusaPure%20Chanca%20Piedra%20200mg%20%7C%20200%20Veggie%20Caps%20%7C%20Herbal%20Extract%20Supplement%20%7C%20Extract%2010%3A1%2C%20Non-GMO%2C%20Bioperine%20%7C%20review),andTrustpilot(https://www.trustpilot.com/search?query=NusaPure%20NusaPure%20Chanca%20Piedra%20200mg%20%7C%20200%20Veggie%20Caps%20%7C%20Herbal%20Extract%20Supplement%20%7C%20Extract%2010%3A1%2C%20Non-GMO%2C%20Bioperine%20%7C).Vyvatadoesnotaggregate,republish,orlicensethosethird-partyreviews.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
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Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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