Optimum Nutrition
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Six-herb sleep/calm blend at 395mg total means each ingredient averages ~66mg — well below therapeutic doses for any of them individually (valerian studied at 400-900mg root extract, passionflower at 350-500mg, hops at 200mg). Per-ingredient breakdown appears to be a proprietary blend without individual dose disclosure. Herb selection is traditional and low-safety-risk, but a six-way split at this total load cannot match single-herb studied protocols. Would move to Standard 62+ with per-ingredient mg disclosure and total dose 800mg+, and reasonably not exceed Standard given the shotgun-blend design.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
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NusaPure Calmme with Valerian Passion Flower Celery Catnip Hops Orange Peel 395 mg 60 Per Tablet Vegetarian/Vegan, Non-GMO is a product from NusaPure, categorized under Sleep supplements & nutraceuticals in the Sleep Optimization vertical. It is scored on the Vyvata Scoring Framework — an independent 6-dimension rubric applied uniformly to every product Vyvata lists.
55/100 overall — Standard tier (50–69 band). Per-dimension breakdown: Safety 62, Evidence 55, Manufacturing 55, Transparency 52, Formulation 48, Sustainability 48. Scored as of 2026-08-24.
Six-herb sleep/calm blend at 395mg total means each ingredient averages ~66mg — well below therapeutic doses for any of them individually (valerian studied at 400-900mg root extract, passionflower at 350-500mg, hops at 200mg). Per-ingredient breakdown appears to be a proprietary blend without individual dose disclosure. Herb selection is traditional and low-safety-risk, but a six-way split at this total load cannot match single-herb studied protocols. Would move to Standard 62+ with per-ingredient mg disclosure and total dose 800mg+, and reasonably not exceed Standard given the shotgun-blend design.
Strongest: Safety at 62/100 (adverse-event profile, interaction risk, and dose ceiling) and Evidence at 55/100 (quality of published RCT support for the active ingredients at the label dose). Weakest: Formulation at 48/100 (dose adequacy, bioavailability form, and ingredient redundancy) and Sustainability at 48/100 (sourcing practices, packaging, and corporate practice). All six dimensions feed the overall Vyvata score; a weakness on any one dimension pulls the overall down proportionally.
No third-party certifications (NSF, USP, ConsumerLab, or equivalent) were on record at the time of scoring. This affects the Manufacturing dimension score. The manufacturer may test internally or have obtained certification more recently — check the current product label for the most up-to-date information.
Would move to Standard 62+ with per-ingredient mg disclosure and total dose 800mg+, and reasonably not exceed Standard given the shotgun-blend design.
The top-ranked sleep supplements & nutraceuticals product in the Vyvata catalog is currently Ortho Molecular Products Botanicalm PM 30 Capsules at 73/100. See the full ranked list of 62 scored products in this subcategory at https://vyvata.com/pages/best-sleep-supplements-and-nutraceuticals-ranked.
The Vyvata Scoring Framework rates every listed product 0–100 across six dimensions: Evidence, Formulation, Manufacturing, Safety, Transparency, and Sustainability. Tier bands: Elite 85–100 (top-tier evidence + formulation + manufacturing), Verified 70–84 (strong on most dimensions), Standard 50–69 (solid but with weaknesses called out), Rejected 0–49 (specific failures documented). Rejected products remain listed with reasons. Full methodology at https://vyvata.com/pages/methodology.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. For customer reviews and community discussion, search external platforms directly: Amazon (https://www.amazon.com/s?k=NusaPure%20NusaPure%20Calmme%20with%20Valerian%20Passion%20Flower%20Celery%20Catnip%20Hops%20Orange%20Peel%20395%20mg%2060%20Per%20Tablet%20Vegetarian%2FVeg),Google(https://www.google.com/search?q=NusaPure%20NusaPure%20Calmme%20with%20Valerian%20Passion%20Flower%20Celery%20Catnip%20Hops%20Orange%20Peel%20395%20mg%2060%20Per%20Tablet%20Vegetarian%2FVeg+reviews),Reddit(https://www.reddit.com/search/?q=NusaPure%20NusaPure%20Calmme%20with%20Valerian%20Passion%20Flower%20Celery%20Catnip%20Hops%20Orange%20Peel%20395%20mg%2060%20Per%20Tablet%20Vegetarian%2FVeg%20review),andTrustpilot(https://www.trustpilot.com/search?query=NusaPure%20NusaPure%20Calmme%20with%20Valerian%20Passion%20Flower%20Celery%20Catnip%20Hops%20Orange%20Peel%20395%20mg%2060%20Per%20Tablet%20Vegetarian%2FVeg).Vyvatadoesnotaggregate,republish,orlicensethosethird-partyreviews.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
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Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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