Optimum Nutrition
THE BIOHACKING STANDARD
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Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
'Hormone' as an ingredient claim on a supplement is a significant regulatory red flag. FDA does not permit supplements to be marketed as hormone therapy — hormone therapy is a prescription-drug regulatory category (estradiol, progesterone, testosterone, thyroid hormones). Supplements that market as 'hormone' products are either (a) using the word loosely to imply hormone-modulating effects (unverified), or (b) actually containing unlabeled hormones (an FDA adulteration concern that has occurred repeatedly with 'female hormone support' products). Additionally, 'vitamin' + 'hormone' compound naming implies functional overlap that does not exist — vitamins don't work like hormones. This SKU discloses no ingredients. Autofailed under unverified_medical_claim (hormone claim without evidence or disclosed ingredients). Rejected at 38.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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