Optimum Nutrition
THE BIOHACKING STANDARD
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Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
Acetyl-L-carnitine (ALCAR) is a real cognitive/energy supplement with moderate evidence for age-related cognitive decline and depression in older adults (Malaguarnera 2007, Am J Clin Nutr; Wang 2014 meta-analysis for depression). It also has modest evidence for peripheral neuropathy (particularly diabetic and chemotherapy-induced). Effective trial doses: 1500-3000mg/day, typically split into 500-1000mg 2-3x/day. Gummy format is a problematic delivery vehicle for ALCAR: (a) each gummy typically holds 100-300mg of active — reaching 1.5-3g/day requires 5-30 gummies; (b) gummies contain 2-4g sugar per piece — 30 gummies is 60-120g of added sugar, comparable to soda; (c) heat-processing gummy manufacture can degrade heat-sensitive amino acid conjugates like ALCAR. 'Biyode' is a generic Chinese OEM brand. Standard 52/100: real ingredient with real evidence, held down by gummy-format subtherapeutic dosing and sugar load, and no per-gummy mg disclosure.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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