Optimum Nutrition
THE BIOHACKING STANDARD
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This SKU stacks three testosterone-narrative ingredients with severe evidence and safety problems: (1) Fadogia agrestis — zero human clinical trials, rodent studies (Yakubu 2005) documented dose-dependent testicular toxicity and kidney damage; (2) Turkesterone — one unpublished (never peer-reviewed) human study, on the WADA 2022 monitoring list, actual androgenic mechanism disputed; (3) Tongkat Ali — has some genuine T-support evidence at 200-400 mg standardized eurycoma, but combined here in an unspecified split. The '1,100 mg' total across three ingredients with no per-ingredient breakdown makes it impossible to know if any is at a meaningful (or safe) dose. 'BestBy10/25' framing suggests a stale-inventory Amazon flip. Autofailed under unverified_medical_claim (T-support without human evidence for two of three ingredients) plus proprietary_blend_hides_dose. Rejected 28.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
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